![]() Methods Twenty patients were enrolled in an unpublished open-label pharmacokinetic–pharmacodynamic study of sodium oxybate for the treatment of essential tremor, conducted by Jazz Pharmaceuticals. ![]() The mean peak-to-peak tremor displacement (cm) in the four spirals and mean FTM ratings were compared statistically. Tremor in each digitized drawing was computed with spectral analysis in an independent laboratory, blinded to the clinical ratings. The drawings were simultaneously digitized with a digitizing tablet. Methods The large and small spirals of FTM were drawn with each hand on two consecutive days by 14 men and four women (age 60☘.7 years ) with mild to severe essential tremor. All basic elements of the device are fixed in its single case which is structurally unites fire-tube the heat recovery system 1, furnace 2, combustion products’ intake tank 3 and gas fuel unit 4. ![]() The device, executed in form box-type structure form, is intended for floor-level installation near the outer wall. IIPHAO>KEHHE RU .00004 K COOTBETCTBHA NQTC CepHARU 0042438 JIHcT 04 nepeqeHb Ha ROTOPYIO pacnpocTpaHgeTcq neiicTBHe cepTHd)HKa.ra COOTBeTCTBHS1.
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